Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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196
Tocris Bioscience™ PFK 15
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective PFKFB3 inhibitor
| CAS | 4382-63-2 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Solubility | Soluble to 100mM in DMSO |
| Purity | >99% |
| Physical Form | Solid |
| Chemical Name or Material | PFK 15 |
| Recommended Storage | Store at -20°C |
| Synonym | 1-(4-Pyridinyl)-3-(2-quinolinyl)-2-propen-1-one |
| Molecular Formula | C17H12N2O |
| Formula Weight | 260.29 |
197
Tocris Bioscience™ (S)-(-)-Carbidopa
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CAS: 28860-95-9 Molecular Formula: C10H14N2O4
| CAS | 28860-95-9 |
|---|---|
| Molecular Formula | C10H14N2O4 |
198
Tocris Bioscience™ ML 365
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Potent and selective K2P3.1 (TASK-1) channel blocker
| Inhibitors | ML 365 |
|---|---|
| Product Type | ML 365 |
| Molecular Weight (g/mol) | 360.41 |
| Purity | >99% |
199
Tocris Bioscience™ 5-Carboxamidotryptamine maleate
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CAS: 74885-72-6 Molecular Formula: C11H13N3O·C4H4O4
| CAS | 74885-72-6 |
|---|---|
| Molecular Formula | C11H13N3O·C4H4O4 |
200
Tocris Bioscience™ ASP 7663
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Selective TRPA1 activator
| CAS | 1190217-35-6 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Solubility | Soluble to 100mM in DMSO and to 100mM in ethanol |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | ASP 7663 |
| Recommended Storage | Store at 4°C |
| Synonym | (2E)-2-[7-Fluoro-1,2-dihydro-1-(2-methylpropyl)-2-oxo-3H-indol-3-ylidene]acetic acid |
| Molecular Formula | C14H14FNO3 |
| Formula Weight | 263.26 |
201
Tocris Bioscience™ LM22B 10
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TrkB and TrkC agonist; brain penetrant
| CAS | 342777-54-2 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 2,2′,2′,2′′′-[[(4-Chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakisethanol |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C27H33ClN2O4 |
202
Tocris Bioscience™ PD 158780
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 171179-06-9 Molecular Formula: C14H12BrN5
| CAS | 171179-06-9 |
|---|---|
| Molecular Formula | C14H12BrN5 |
203
Tocris Bioscience™ AMG 333
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Potent and selective TRPM8 antagonist
| Product Type | Antagonist |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C20H12F5N3O4 |
| Formula Weight | 453.33 |
204
Tocris Bioscience™ MO-I-500
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FTO inhibitor; anticonvulsant
| Target | Other Oxidase/Oxygenase Compounds |
|---|---|
| CAS | 1585219-04-0 |
| Purity | 0.98 |
| Chemical Name or Material | N-[5-(4-Chlorophenyl)-3,4-dihydroxy-2-furanyl]ethanesulfonamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C12H12ClNO5S |
205
Tocris Bioscience™ (+)-Igmesine hydrochloride
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Selective sigma1 ligand; antidepressant
| CAS | 130152-35-1 |
|---|---|
| Solubility | Soluble to 50mM in DMSO |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C23H29N.HCl |
| Formula Weight | Observed MW: 355.94 |
| Assay Percent Range | >98% |
206
Tocris Bioscience™ Apcin
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Cdc20 inhibitor; inhibits Cdc20-substrate interaction
| Target | Ubiquitin Ligase (E3) Inhibitors |
|---|---|
| CAS | 300815-04-7 |
| Purity | >98% |
| Chemical Name or Material | 3-(2-Methyl-5-nitroimidazol-1-yl)-N-(2,2,2-trichloro-1-phenylaminoethyl)propionamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C13H14Cl3N7O4 |
| Formula Weight | 438.65 |
207
Tocris Bioscience™ JNJ 16259685
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CAS: 409345-29-5 Molecular Formula: C20H23NO3
| CAS | 409345-29-5 |
|---|---|
| Molecular Formula | C20H23NO3 |
208
Tocris Bioscience™ NNMTi
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Nicotinamide N-methyltransferase (NNMT) inhibitor; promotes myoblast differentiation
| CAS | 42464-96-0 |
|---|---|
| Purity | 97% |
| Chemical Name or Material | 5-Amino-1-methylquinolinium iodide |
| Molecular Formula | C10H11IN2 |
209
Tocris Bioscience™ VH 032 amide-alkylC10-amine
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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VH 032-alkylC10-amine
210
Tocris Bioscience™ Terfenadine
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CAS: 50679-08-8 Molecular Formula: C32H41NO2
| CAS | 50679-08-8 |
|---|---|
| Molecular Formula | C32H41NO2 |